Patrick Hearing Selected Research

Viral DNA

10/2019	An Interaction with PARP-1 and Inhibition of Parylation Contribute to Attenuation of DNA Damage Signaling by the Adenovirus E4orf4 Protein.
6/2017	The adenovirus major core protein VII is dispensable for virion assembly but is essential for lytic infection.
10/2012	The adenovirus L4-22K protein is multifunctional and is an integral component of crucial aspects of infection.
5/2009	Temporal regulation of the Mre11-Rad50-Nbs1 complex during adenovirus infection.
5/2005	Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication.

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Patrick Hearing Research Topics

Disease

23	Infections 03/2023 - 05/2005
7	Virus Diseases (Viral Diseases) 01/2016 - 05/2003
6	Neoplasms (Cancer) 03/2023 - 10/2010
3	Adenoviridae Infections (Adenovirus Infections) 01/2016 - 05/2003
2	Inflammation (Inflammations) 05/2024 - 01/2016
2	Thrombocytosis (Thrombocythemia) 01/2022 - 12/2008
2	Persistent Infection 01/2022 - 01/2020
2	Leukemia 01/2020 - 04/2007
2	Hemophilia A (Haemophilia) 12/2008 - 08/2004
1	Colitis 05/2024
1	Ulcerative Colitis 05/2024
1	Kaposi Sarcoma (Kaposi's Sarcoma) 03/2023
1	Retinoblastoma (Glioblastoma, Retinal) 01/2022
1	COVID-19 12/2021
1	RNA Virus Infections 12/2021
1	Bites and Stings (Sting) 12/2021
1	Zika Virus Infection 01/2020
1	Plague (Bubonic Plague) 09/2016
1	Breast Neoplasms (Breast Cancer) 08/2011
1	Stroke (Strokes) 06/2011
1	Coinfection 11/2002

Drug/Important Bio-Agent (IBA)

22	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2005
8	InterferonsIBA 03/2023 - 05/2007
5	Antiviral Agents (Antivirals)IBA 12/2021 - 01/2016
5	Viral DNAIBA 10/2019 - 05/2005
4	A-Form DNA (A-DNA)IBA 12/2021 - 05/2011
3	DNA (Deoxyribonucleic Acid)IBA 10/2019 - 11/2002
2	Viral Core ProteinsIBA 06/2017 - 05/2011
2	Viral ProteinsIBA 01/2016 - 01/2011
2	adenovirus L4-22K proteinIBA 07/2013 - 10/2012
2	Folic Acid (Vitamin M)FDA LinkGeneric 08/2011 - 10/2010
2	Factor VIII (Coagulation Factor VIII)IBA 12/2008 - 08/2004
1	Tn antigenIBA 05/2024
1	Interleukin-22 (IL-22)IBA 05/2024
1	MucinsIBA 05/2024
1	Polysaccharides (Glycans)IBA 05/2024
1	Dextran SulfateIBA 05/2024
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 03/2023
1	Histone Deacetylase InhibitorsIBA 01/2022
1	NucleotidesIBA 01/2022
1	Cyclin-Dependent Kinase 4IBA 01/2022
1	CytokinesIBA 01/2022
1	Angiotensin-Converting Enzyme 2IBA 12/2021
1	Interferon LambdaIBA 12/2021
1	Glycoproteins (Glycoprotein)IBA 01/2020
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 10/2019
1	HeterochromatinIBA 01/2019
1	DNA-Activated Protein KinaseIBA 01/2019
1	Type III Secretion SystemsIBA 09/2016
1	InflammasomesIBA 09/2016
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	ChromatinIBA 01/2016
1	Trans-Activators (Trans-Acting Factor)IBA 01/2016
1	HMGB1 Protein (HMG1)IBA 01/2016
1	Tyrosine (L-Tyrosine)FDA Link 08/2011
1	Protein Tyrosine PhosphatasesIBA 08/2011
1	Adenosine Triphosphatases (ATPase)IBA 06/2011
1	Capsid Proteins (Capsid Protein)IBA 01/2011
1	Platelet Factor 4IBA 12/2008
1	Nuclear Proteins (Protein, Nuclear)IBA 04/2007
1	Arginine (L-Arginine)FDA Link 02/2005
1	AcetyltransferasesIBA 05/2003
1	Adenovirus Early ProteinsIBA 05/2003